Date: August 28, 2010
Venue: TD Garden
City: Boston, Massachusetts, USA
Preliminary card
- Welterweight bout: Mike Pierce vs. Amilcar Alves
- Pierce defeated Alves via submission (straight armbar) at 3:11 of round 3.
- Welterweight bout: Nick Osipczak vs. Greg Soto
- Soto defeated Osipczak via unanimous decision (29-28, 29-28, 29-28).
- Middleweight bout: Dan Miller vs. John Salter
- Miller defeated Salter via submission (ninja choke) at 1:53 of round 2. This bout aired on the Spike broadcast following the Lauzon vs. Ruediger fight.
Preliminary card (Spike TV)
- Lightweight bout: Andre Winner vs. Nik Lentz
- Lentz defeated Winner via unanimous decision (30-27, 29-28, 30-27).
- Lightweight bout: Joe Lauzon vs. Gabe Ruediger
- Lauzon defeated Ruediger via submission (armbar) at 2:01 of round 1. This bout aired last on the PPV broadcast following the Edgar vs. Penn fight.
Main card
- Welterweight bout: Nate Diaz vs. Marcus Davis
- Diaz defeated Davis via technical submission (guillotine choke) at 4:02 of round 3.
- Lightweight bout: Kenny Florian vs. Gray Maynard
- Maynard defeated Florian via unanimous decision (30-27, 30-27, 30-27).
- Middleweight bout: Demian Maia vs. Mario Miranda
- Maia defeated Miranda via unanimous decision (30-27, 30-27, 30-27).
- Heavyweight bout: Randy Couture vs. James Toney
- Couture defeated Toney via submission (arm triangle choke) at 3:19 of round 1.
- Lightweight Championship bout: Frankie Edgar (c) vs. B.J. Penn
- Edgar defeated Penn via unanimous decision (50-45, 50-45, 50-45) to retain the UFC Lightweight Championship.
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