Date: November 12, 2011
Venue: Honda Center
City: Anaheim, California

Preliminary card (Facebook and FoxSports.com)

  • Light Heavyweight bout:  Aaron Rosa vs.  Matt Lucas
Rosa defeated Lucas via majority decision (28–28, 30–26, 30–26). Lucas was deducted one point in the second round for repeatedly dropping his mouthpiece.
  • Welterweight bout:  Mike Pierce vs.  Paul Bradley
Pierce defeated Bradley via split decision (29–28, 30–27, 28–29).
  • Bantamweight bout:  Alex Caceres vs.  Cole Escovedo
Caceres defeated Escovedo via unanimous decision (30–27, 30–27, 30–27).
  • Featherweight bout:  Mackens Semerzier vs.  Robert Peralta
Peralta defeated Semerzier via TKO (punches) at 1:54 of round 3.
  • Bantamweight bout:  Norifumi Yamamoto vs.  Darren Uyenoyama
Uyenoyama defeated Yamamoto via unanimous decision (30–27, 30–26, 30–27).
  • Welterweight bout:  DaMarques Johnson vs.  Clay Harvison
Johnson defeated Harvison via TKO (punches) at 1:34 of round 1.
  • Featherweight bout:  Cub Swanson vs.  Ricardo Lamas
Lamas defeated Swanson via submission (arm triangle choke) at 2:16 of round 2.
  • Featherweight bout:  Dustin Poirier vs.  Pablo Garza
Poirier defeated Garza via submission (D’Arce choke) at 1:32 of round 2.
  • Lightweight bout:  Benson Henderson vs.  Clay Guida
Henderson defeated Guida via unanimous decision (29–28, 30–27, 30–27).

Main event

  • Heavyweight Championship bout:  Cain Velasquez (c) vs.  Junior dos Santos
Dos Santos defeated Velasquez via KO (punches) at 1:04 of round 1 to become the new UFC Heavyweight Champion.

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